DENVER, COLORADO – March 18, 2026 – As Colorado continues to lead the nation in progressive psychedelic legislation under the Natural Medicine Health Act (NMHA), a groundbreaking Denver-based platform is setting the global standard for safety, education, and integration. Mushrooms.support, operating under Lyman Support Centers LLC, has officially announced the expansion of its comprehensive ecosystem dedicated to harm reduction, non-commercial gifting, and guided support for adults exploring the therapeutic benefits of psilocybin and dimethyltryptamine (DMT).
Following the historic voter approval of Proposition 122 and subsequent SB23-290 refinements, Colorado decriminalized the personal use, possession, and sharing of natural medicines for adults over 21. Navigating this new legal landscape, Mushrooms.support emerges as a vital community hub. Operating strictly within the non-commercial parameters of the law, the platform facilitates the free gifting of psilocybin and DMT while offering paid, professionally guided harm reduction sessions ranging from an accessible $10 to $200. This model ensures that life-changing mental health support and safety are accessible to all demographics, effectively removing the financial barriers often associated with psychedelic-assisted care.
The Scientific Foundation of Therapeutic Psychedelics The platform’s mission is deeply rooted in cutting-edge clinical research. Recent phase III trials and landmark studies from institutions like Johns Hopkins University have demonstrated the profound efficacy of psilocybin in treating Major Depressive Disorder (MDD), Treatment-Resistant Depression (TRD), and end-of-life existential anxiety.
By acting as a serotonin 5-HT2A receptor agonist, psilocybin promotes neuroplasticity, helping to rewire maladaptive thought patterns. Similarly, emerging research highlights endogenous DMT’s potential as a rapid-acting antidepressant and neuroprotectant. Mushrooms.support translates this complex science into actionable guidance for individuals dealing with PTSD, OCD, cluster headaches, and substance use disorders.
Award-Winning Harm Reduction Principles Recognized as the “Psychedelic Cup 2025 Winner” and awarded “Most Homogeneous” for its consistent quality and safety standards, Mushrooms.support distinguishes itself through five core principles of harm reduction:
1. Rigorous Testing: Ensuring the purity and safety of natural medicines.
2. Comprehensive Education: Providing transparent data on physiological effects and risks.
3. Set and Setting Preparation: Guiding users to create optimal environments for psychological safety.
4. On-Site Guided Support: Offering trained presence during the experience.
5. Post-Experience Integration: Helping users process and apply their insights for long-term personal growth.
Trained ambassadors and medical referrals are available to ensure that every individual’s journey is safe and therapeutically beneficial. The platform also strictly educates on contraindications, prominently warning against the risks of serotonin syndrome for individuals on specific medications or those with underlying cardiovascular or psychotic conditions.
“Decriminalization is only the first step; the true evolution of mental health care requires a solid foundation of safety, education, and community support,” says Darren Lyman, founder of Mushrooms.support and author of foundational texts on psychedelic integration. “Our goal is to transform Colorado’s legal framework into a scientifically grounded, accessible public health strategy. We are providing the essential resources—from microdosing guides to post-session integration—so individuals can explore these powerful natural medicines without fear or stigma.”
A Comprehensive Community Ecosystem Beyond one-on-one support, the Denver facility (located at 800 W. 8th Ave #110) and its digital platform offer an expansive library of resources. Users can access microdosing protocols, integration workbooks, specialized PDF drink recipes, chocolate formulations, and connections to trusted community growers and wellness products like Epic Balms.
As the psychedelic renaissance accelerates in 2026, Mushrooms.support stands at the forefront of the movement, ensuring that the integration of psilocybin and DMT into mainstream wellness is conducted ethically, safely, and equitably.
For more information, to access harm reduction resources, or to schedule a session, visit Website.
About Mushrooms.support
Mushrooms.support is a Denver-based educational and harm reduction platform operating under the Colorado Natural Medicine Health Act. Founded by Darren Lyman and managed by Lyman Support Centers LLC, the center provides non-commercial gifting of natural medicines alongside expert-guided support, integration services, and scientific resources for adults 21 and older. Operations run Tuesday through Saturday from 2:00 PM to 6:45 PM.
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Disclaimer: This press release is for informational purposes only. Statements regarding therapeutic effects of psilocybin and DMT are based on research and do not constitute medical advice. Individuals should consult qualified healthcare professionals before using these substances.
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